Wentworth-Douglass Hospital
(603) 742-5252
Decrease (-) Restore Default Increase (+) font size
Physicians
Health Library
Back to Health Library   Print This Page Print    Email to a Friend Email

Kidney anatomy
Kidney anatomy


Definition:

Chronic glomerulonephritis is the advanced stage of a group of kidney disorders, resulting in inflammation and slowly worsening destruction of internal kidney structures called glomeruli.



Alternative Names:

Glomerulonephritis - chronic; Chronic nephritis



Causes, incidence, and risk factors:

Chronic glomerulonephritis occurs when there is slow, progressive destruction of the glomeruli of the kidney, with progressive loss of kidney function. In some cases, the cause is found to be a specific attack to the body's immune system, but in most cases, the cause is unknown. Iit is generally thought that a still-unidentified abnormality of the immune system is to blame.

Damage to the glomeruli affects the kidney's ability to filter fluids and wastes properly. This leads to blood and protein in the urine.

This condition may develop after survival of the acute phase of rapidly progressive glomerulonephritis . In about one-quarter of people with chronic glomerulonephritis there is no prior history of kidney disease , and the disorder first appears as chronic kidney failure.

Glomerulonephritis is among the leading causes of chronic kidney failure and end stage kidney disease. Causes include:



Symptoms:

This condition causes high blood pressure (hypertension) and chronic kidney failure .

Specific symptoms include:

Chronic kidney failure symptoms that gradually develop may include the following:

Additional symptoms that may be associated with this disease:



Signs and tests:

Because symptoms develop gradually, the disorder may be discovered when there is an abnormal urinalysis during a routine physical or during an examination for another, unrelated disorder. It may be discovered as a cause of high blood pressure that is difficult to control.

Laboratory tests may reveal anemia or show signs of reduced kidney functioning, including azotemia . Later, signs of chronic kidney failure may be apparent, including edema .

Tests that may be done include:

A kidney biopsy may show one of the forms of chronic glomerulonephritis or scarring of the glomeruli.

This disease may also alter the results of the following tests:



Treatment:

Treatment varies depending on the cause of the disorder, and the type and severity of symptoms. The primary treatment goal is control of symptoms. High blood pressure may be difficult to control, and it is generally the most important aspect of treatment. Various medications may be used to attempt to control high blood pressure.

Corticosteroids, immunosuppressives, or other medications may be used to treat some of the causes of chronic glomerulonephritis.

Dietary restrictions on salt, fluids, protein , and other substances may be recommended to help control of high blood pressure or kidney failure.

Dialysis or kidney transplantation may be necessary to control symptoms of kidney failure and to sustain life.



Support Groups:

For information and support, see kidney disease support groups .



Expectations (prognosis):

The outcome varies depending on the cause. Some types of glomerulonephritis may get better on their own.

If nephrotic syndrome is present and can be controlled, other symptoms may be controlled. If nephrotic syndrome is present and cannot be controlled, end-stage kidney disease is likely.

The disorder worsens at widely variable rates.



Calling your health care provider:

Call your health care provider if disorders associated with increased risk of chronic glomerulonephritis are present, or if symptoms indicating glomerulonephritis develop.



Prevention:

There is no specific prevention for most cases of chronic glomerulonephritis. Some cases may be prevented by avoiding or limiting exposure to organic solvents, mercury , and nonsteroidal anti-inflammatory analgesics.




Review Date: 8/14/2007
Reviewed By: Charles Silberberg, DO, Private Practice specializing in Nephrology, Affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com


Find What You Need

Events
Careers
Foundation
About Us
Contact
Directions
News
Social Media Agreement
Joint Notice
Web Privacy Policy
WDH Staff Portal

Centers & Services

Cancer Center
Cardiovascular Care
Joint Replacement
Women & Children's
Physician Offices
Other Services

Conditions & Treatments

Health Library

Support Services

Support Groups
Care-Van
Dental Center
Social Work
Food & Nutrition
Integrative Wellness
Spiritual Care
Concerns & Grievances
Homecare and Hospice

For Patients

Pay Your Bill Online
Pricing Estimates
Financial Assistance
Interpreter Services
Surgery Preparation
Medical Record Request
Advance Directives
Clinical Research & Trials

For Healthcare Professionals

Work and Life
Financial Well-Being
Career and Growth

The Wentworth-Douglass Health System includes:

 

Address

Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100