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Ovalocytoses
Ovalocytoses


Blood cells
Blood cells


Definition:

Hereditary ovalocytosis is rare condition passed down through families (inherited) in which blood cells are slightly oval-shaped instead of round. It is a form of hereditary elliptocytosis .



Alternative Names:

Ovalocytosis - hereditary



Causes, incidence, and risk factors:

Ovalocytosis is mainly found in Southeast Asian populations.



Symptoms:

Newborn infants with ovalocytosis may have anemia and jaundice. Adults usually do not show symptoms and are known as asymptomatic.



Signs and tests:

An examination by your health care provider may occasionally show an enlarged spleen.

This condition is diagnosed by looking at the shape of blood cells under a microscope. The following tests may also be done:



Treatment:

In severe cases, the disease may be treated by removal of the spleen (splenectomy ).



Support Groups:



Expectations (prognosis):



Complications:

The condition may be associated with gallstones or kidney problems.



Calling your health care provider:



Prevention:



References:

Jeng MR. Hematologic problems in immigrants from Southeast Asia. Hematol Oncol Clin North Am. Dec 2004;18(6):1405-22, x.

Laosombat V, Dissaneevate S, Wongchanchailert M, Satayasevanaa B. Neonatal anemia associated with Southeast Asian ovalocytosis. Int J Hematol. 2005 Oct;82(3):201-5.




Review Date: 11/10/2008
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100