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Normal anatomy:

The heart is located in the chest cavity, or thorax. It pumps blood from the lungs to the rest of the body.


Normal anatomy


Indications:

A heart transplant may be recommended for heart failure caused by:

  • coronary artery disease
  • cardiomyopathy (thickening of the heart walls)
  • heart valve disease with congestive heart failure
  • severe congenital heart disease

Heart transplant surgery is not recommended for patients who have:

  • kidney, lung, or liver disease
  • insulin-dependent diabetes mellitus (IDDM)
  • other life-threatening diseases

Indications


Procedure:

Heart transplants are the third most common (corneas and kidneys are the most common) transplant operations in the U.S. (over 1,500 cases per year). A healthy heart is obtained from a donor who has suffered brain death but remains on life-support. The healthy heart is transported in a special solution that preserves the organ. While the patient is deep asleep and pain-free (general anesthesia), an incision is made through the breast bone (sternum). The patient's blood is re-routed through tubes to a heart-lung bypass machine to keep the blood oxygen-rich and circulating. The patient's diseased heart is removed and the donor heart is stitched in place.


Procedure


Aftercare:

Heart transplant prolongs the life of a patient who otherwise would die. About 80% of heart transplants are alive two years after the operation. The main problem, as with other transplants, is graft rejection. If rejection can be controlled, then survival can be increased up to 10 years or more. Immunosuppressive drugs must be taken indefinitely. Relatively normal activities can resume as soon as the patient feels well enough and after consulting with his or her doctor. However, vigorous physical activities should be avoided.

The major problems are the same all major organ transplants face:

  • a shortage of donor hearts
  • rejection of the transplanted heart
  • cost of the surgery and post-operative care, including immunosuppressive drugs

Aftercare



Review Date: 7/25/2007
Reviewed By: Robert A. Cowles, MD, Assistant Professor of Surgery, Columbia University College of Physicians and Surgeons, New York, NY. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100