Wentworth-Douglass Hospital
(603) 742-5252
Decrease (-) Restore Default Increase (+) font size
Physicians
Site Search

Definition:

Tartrate resistant acid phosphatase (TRAP) is a test performed on blood cells or bone marrow (biopsy) to confirm a diagnosis of hairy cell leukemia. This test can also be done on blood plasma to look for signs of bone breakdown, for example to measure bone destruction caused by cancer.



Alternative Names:

Type 5 acid phosphatase test; TRAP test



How the test is performed:

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

This test also can be done on a bone marrow biopsy .



How to prepare for the test:

No special preparation is needed for the blood test.



How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.



Why the test is performed:

Your doctor may order this test if you have signs of hairy cell leukemia. Hairy cell leukemia is a type of blood cancer in which TRAP levels are very high.

This test may also be done to monitor the activity of cancers that have spread to your bones. These cancers include multiple myeloma, and breast, lung, or prostate cancers. However, the test is not yet widely used for this purpose.



Normal Values:

There should be less than 5 nanogram per milliliter (ng/mL) of acid phosphatase in the presence of tartrate.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.



What abnormal results mean:

A high level of TRAP in leukemia cells supports a diagnosis of hairy cell leukemia.

A high level of TRAP in the blood plasma is a sign of bone breakdown. This can be due to many types of diseases, but in a patient with cancer it is likely a sign that the cancer has spread to bone.



What the risks are:

There is very little risk involved with having your blood taken. Veins and arteries vary in size from one patient to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.

Other risks associated with having blood drawn are slight but may include:

  • Excessive bleeding
  • Fainting or feeling light-headed
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)


Special considerations:

This test is less often used to diagnose hairy cell leukemia because now there is a method to identify cells based on types of markers found on the cell surface (immunophenotyping).




Review Date: 7/11/2008
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com


Find What You Need

Events
Careers
Foundation
About Us
Contact
Directions
News
Social Media Agreement
Joint Notice
Web Privacy Policy
WDH Staff Portal

Centers & Services

Cancer Center
Cardiovascular Care
Joint Replacement
Women & Children's
Physician Offices
Other Services

Conditions & Treatments

Health Information
Ebola Information

Support Services

Support Groups
Care-Van
Dental Center
Social Work
Food & Nutrition
Integrative Wellness
Spiritual Care
Concerns & Grievances
Homecare and Hospice

For Patients

Pay Your Bill Online
Pricing Estimates
Financial Assistance
Interpreter Services
Surgery Preparation
Medical Record Request
Advance Directives
Clinical Research & Trials

For Healthcare Professionals

Work and Life
Financial Well-Being
Career and Growth

The Wentworth-Douglass Health System includes:

 

Address

Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100