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Dermatomyositis, Gottron's papule
Dermatomyositis, Gottron's papule

Dermatomyositis, heliotrope eyelids
Dermatomyositis, heliotrope eyelids

Dermatomyositis on the legs
Dermatomyositis on the legs

Dermatomyositis, Gottron's papule
Dermatomyositis, Gottron's papule

Polyarteritis, microscopic on the shin
Polyarteritis, microscopic on the shin

Systemic lupus erythematosus rash on the face
Systemic lupus erythematosus rash on the face


Collagen is a tough, glue-like protein that makes up 30% of body protein. It shapes the structure of tendons, bones, and connective tissues. Problems with the immune system can affect these structures. This is known as collagen vascular disease.

Collagen vascular diseases include:

Causes, incidence, and risk factors:


Symptoms of collagen vascular disease may include:

  • Anemia
  • Fever
  • Joint inflammation
  • Weakness

Signs and tests:


Support Groups:

Expectations (prognosis):


Calling your health care provider:


Review Date: 2/22/2009
Reviewed By: Ariel D. Teitel, MD, MBA, Chief, Division of Rheumatology, St. Vincent’s Hospital, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100