Wentworth-Douglass Hospital
(603) 742-5252
Decrease (-) Restore Default Increase (+) font size
Physicians
Site Search

Secretin stimulation test
Secretin stimulation test


Definition:

The secretin stimulation test measures the ability of the pancreas to respond to a hormone called secretin. Secretin is produced by the small intestine when partially digested food has moved into the area from the stomach.



Alternative Names:

Pancreatic function test



How the test is performed:

A tube is inserted through the nose and into the stomach, then into the the first part of the small intestine ( duodenum ). Secretin is given through this tube. Then, over the next 2 hours or so, the contents of the material released from the duodenum are removed through the tube.



How to prepare for the test:

You will be asked to not eat or drink anything, including water, for 12 hours prior to the test.



How the test will feel:

You may experience a gagging sensation as the tube is inserted.



Why the test is performed:

Secretin normally causes the pancreas to release a fluid containing digestive enzymes. These enzymes break down food and help in the absorption of nutrients.

The secretin stimulation test is done to check the function of the pancreas in digestion. People with diseases involving the pancreas may have abnormal pancreatic function. Such diseases include chronic pancreatitis , cystic fibrosis , and pancreatic cancer .

In people with cystic fibrosis, the pancreas may form mucus plugs. These plugs block the ducts that lead from the pancreas into the small intestine. This prevents the food acidity from being neutralized, and ultimately reduces the ability of the body to digest food and absorb nutrients.



Normal Values: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean:

Abnormal values may indicate cystic fibrosis or chronic pancreatitis .



What the risks are:

There is a slight risk of the tube being placed through the windpipe and into the lungs, instead of through the esophagus and into the stomach. The health care provider will be sure the tube is correctly placed before continuing with the test.



Special considerations:



References:

Jensen RT. Pancreatic endocrine tumors. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 205.

Semrad CE, Powell DW. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 143.




Review Date: 11/2/2008
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com


Find What You Need

Events
Careers
Foundation
About Us
Contact
Directions
News
Social Media Agreement
Joint Notice
Web Privacy Policy
WDH Staff Portal

Centers & Services

Cancer Center
Cardiovascular Care
Joint Replacement
Women & Children's
Physician Offices
Other Services

Conditions & Treatments

Health Information
Ebola Information

Support Services

Support Groups
Care-Van
Dental Center
Social Work
Food & Nutrition
Integrative Wellness
Spiritual Care
Concerns & Grievances
Homecare and Hospice

For Patients

Pay Your Bill Online
Pricing Estimates
Financial Assistance
Interpreter Services
Surgery Preparation
Medical Record Request
Advance Directives
Clinical Research & Trials

For Healthcare Professionals

Work and Life
Financial Well-Being
Career and Growth

The Wentworth-Douglass Health System includes:

 

Address

Wentworth-Douglass Hospital
789 Central Avenue, Dover, NH 03820
Phone: (603) 742-5252
Toll free: 1 (877) 201-7100